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Separate Biology · Paper 1 · Higher Tier only

Making monoclonal antibodies

Key ideas1 of 4

One clone, one antibody

Monoclonal antibodies come from one clone of cells. Their binding sites are the same, so they bind to the same specific antigen. An antigen is a molecule recognised by an antibody, often on a cell or pathogen.

A Y-shaped antibody and a cell with particular surface antigens. Only a matching binding site fits an antigen.

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Practice, downloads and sources

Daily 5 · Exam practice · Revision sheet ↓

Higher Tier only. Use alongside the shared B1–B4 lessons.

AQA GCSE Biology 8461 · 4.3.2.1–4.3.2.2. Original teaching notes, questions and diagrams.